This is largely the methodology I've used throughout my career - that is, starting with a question as to what might be the properties of a set of compounds that could be invented which were unusual and unpredictable. Many times I've felt a bit like Columbus setting sail.

这在很大程度上是我在整个职业生涯中所使用的方法——也就是说，从一个问题开始，即一组可以被发明出来的不同寻常和不可预测的化合物的属性可能是什么。很多时候，我觉得自己有点像哥伦布起航了。